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Vigamox Eye Drops |
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Vigamox Structure
- 0.5% - moxifloxacin hydrochloride ophthalmic solution;
Vigamox Indications
Vigamox eye drops are indicated for the treatment of bacterial conjunctivitis caused by susceptible
strains of the following organisms:
Aerobic Gram-positive microorganisms:
- Streptococcus viridans group;
- Streptococcus pneumoniae;
- Staphylococcus warneri;
- Staphylococcus hominis;
- Staphylococcus haemolyticus;
- Staphylococcus epidermidis;
- Staphylococcus aureus;
- Micrococcus luteus;
- Corynebacterium species;
Aerobic Gram-negative microorganisms:
- Haemophilus parainfluenzae;
- Haemophilus influenzae;
- Acinetobacter lwoffii;
Other microorganisms:
- Chlamydia trachomatis;
Vigamox Contraindications
Vigamox eye drops are contraindicated in patients with a history of hypersensitivity to moxifloxacin, to
other quinolones, or to any of the components in Vigamox eye drops.
Vigamox and Pregnancy
Vigamox eye drop was not teratogenic when administered to pregnant rats during organogenesis at oral
doses as high as 500 mg/kg/day (approximately 21,700 times the highest recommended total daily human ophthalmic dose);
however, decreased fetal body weights and slightly delayed fetal skeletal development were observed. There was no evidence
of teratogenicity when pregnant Cynomolgus monkeys were given oral doses as high as 100 mg/kg/day (approximately 4,300
times the highest recommended total daily human ophthalmic dose). An increased incidence of smaller fetuses was observed
at 100 mg/kg/day.
Vigamox and Nursing Mothers
Vigamox eye drop has not been measured in human milk, although it can be presumed to be excreted in human
milk. Caution should be exercised when Vigamox eye drops are administered to a nursing mother.
Vigamox Side Effects
The most frequently reported ocular adverse events were:
- Tearing;
- Subconjunctival hemorrhage;
- Ocular pruritus;
- Ocular pain;
- Ocular hyperemia;
- Ocular discomfort;
- Keratitis;
- Dry eye;
- Decreased visual acuity;
- Conjunctivitis;
These events occurred in approximately 1-6% of patients.
Nonocular adverse events reported at a rate of 1-4% were:
- Rhinitis;
- Rash;
- Pharyngitis;
- Otitis media;
- Infection;
- Increased cough;
- Fever;
Vigamox Dosage
Instill 1 drop in the affected eye 3 times a day for 7 days.
Vigamox Form
- 3 mL bottle
- 4 mL bottle
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Ciplox