Eye drops


Tobrex

Where to buy Tobrex ?

Structure

- 3mg - Tobramycin sulphate USP;
- 0.04mg Benzalkonium Chloride USP;

Indications

Tobrex eye drops are a topical antibiotic formulation indicated in the treatment of external infections of the eye and its adnexa caused by susceptible bacteria. Appropriate monitoring of bacterial response to topical antibiotic therapy should accompany the use of Tobrex eye drops.

Contraindications

Tobrex eye drops are contraindicated in patients with known hypersensitivity to any ingredient in the drug.

Pregnancy

Reproduction studies in animals using Tobrex eye drops doses up to 33 times the normal human systemic dose have not revealed evidence of impaired fertility or harn to foetus. There are, however, no control studies to date using Tobrex eye drops in pregnant women and Tobrex eye drops should be used during pregnancy only when clearly needed.

Nursing Mothers

Because of the potential for serious adverse reactions from the drug in nursing infants, Tobrex eye drops should not normally be used in nursing women.
A decision should be made whether to discontinue nursing or discontinue Tobrex eye drops, taking into account the importance of the medicine to the mother.

Side Effects

Tobrex eye drops appears to have low order of toxicity when applied topically to the eye. However, sensitisation to Tobrex eye drops may occasionally result from topical application. If a sensitive reaction occurs during Tobrex eye drop therapy, the drop should be discontinued. The most frequent adverse reactions to Tobrex eye drops are:
- Conjunctival erythema;
- Eyelid;
- Hypersensitivity;
- Increased lacrimation;
- Itching and edema;
- Localized ocular toxicity;

These reactions occur in less than 3% of patients receiving Tobrex eye drops and usually disappear when the drop is discontinued. Punctate keratitis has also been reported following excessive application of Tobrex.

Dosage

For mild to moderate infections, 1 or 2 drops of Tobrex eye drop should be instilled into the infected eye(s) every 4 hours. In severe infections, including Pseudomonas aeruginosa infections, 2 drops of the solution should be instilled into the infected eye(s) every hour initially. When improvement occurs, frequency of application can be decreased. Therapy should be continued for at least 48 hours after the infection has been controlled.

Overdosage

Clinically apparent signs and symptoms of an overdose of Tobrex eye drop may be similar to adverse reactions seen in some patients:
- Edema;
- Erythema;
- Increased lacrimation;
- Lid itching;
- Punctate keratitis;

Form

Tobrex eye drops are available in 5 ml plastic dropper bottles.

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