Eye drops


Restasis

Where to buy Restasis ?

Structure

- 0.05% - cyclosporine ophthalmic emulsion;

Indications

Restasis eye drops are indicated to increase tear production in patients whose tear production is presumed to be suppressed due to ocular inflammation associated with keratoconjunctivitis sicca. Increased tear production was not seen in patients currently taking topical anti-inflammatory drugs or using punctal plugs.

Contraindications

Restasis eye drops are contraindicated in patients with active ocular infections and in patients with known or suspected hypersensitivity to any of the ingredients in the formulation.

Pregnancy

No evidence of teratogenicity was observed in rats or rabbits receiving oral doses of cyclosporine up to 300 mg/kg/day during organogenesis. These doses in rats and rabbits are approximately 300,000 times greater than the daily human nose of one drop (28 ml) 0.05% Restasis eye drops BID into each eye of a 60 kg person (0.001 mg/kg/day), assuming that the entire dose is absorbed.

Side effects were seen in reproduction studies in rats and rabbits only at dose levels toxic to dams At toxic doses (rats at 30 mg/kg/day and rabbits at 100 mg/kg/day), cyclosporine oral solution, USP, was embryo and fetotoxic as indicated by increased pre- and postnatal mortality and reduced fetal weight together with related skeletal retardaiions.

Nursing Mothers

Restasis eye drops are known to be excreted in human milk following systematic administration but excretion in milk after topical treatment has not been investigated. Although blood concentrations are undetectable after topical administration of Restasis eye drops, caution should be exercised when Restasis eye drops are administered to a nursing woman,

Side Effects

The most common adverse event following the use of Restasis eye drops was ocular burning (17%).
Other events reported in 1% to 5% of patients included:
- Visual disturbance (most often blurring);
- Stinging;
- Pruritus;
- Foreign body sensation;
- Eye pain;
- Epiphora;
- Discharge;
- Conjunctival hyperemia;

Dosage

Invert the unit dose vial a few times to obtain a uniform, white, opaque emulsion before using. Instill one drop of Restasis eye drop twice a day in each eye approximately 12 hours apart. Restasis eye drop can be prescribed concomitantly with artificial tears, allowing a 15 minute interval between products. Discard vial immediately after use.

Form

Restasis eye drops are packaged in single use vials. Each vial contains 0.4 mL fill in a 0.9 mL LOPE vial: 32 vials are packaged in a polypropylene tray with an aluminium peelable lid.

Antibiotics
Brulamycin
Ciloxan
Ciplox
Cipmox
Garamycin
Maxitrol
Ocuflox
Sofracort
Soframycin
Tobrex
Vigamox
Zymar
Antihistamine
Alergoftal
Allergo Comod
Cromolux
Ketotifen
Livostin
Opatanol
Patanol
Zaditor
Corticosteroids
Flomex
FML
Fluorometholone
Loteflam
Pred Forte
Decongestants
Albalon
Glaucoma
Allergan
Alphagan
Azopt
Azoptic
Betagan
Betaxolol
Betoptic
Bimatoprost
Brimodin P
Brimonidine
Combigan
Cosopt
Dorzolamide
Dorzox
Isopto
Latim
Lumigan
Pilagan
Pilopt
Phospholine Iodide
Timolol
Timoptic
Timpilo
Travatan
Trusopt
Xalacom
Xalatan
Mast cell stabilizers
Crolom
Cromal
Epina
NSAID
Acular
Acularen
Cyclosporine
Sodium Sulamyd
Others
Adsorbonac
Celluvisc
Cyclogyl
Epinastine
Flur
Flarex
Glaucoprost
Iobrim
Iotim
Methopt
Mydriacyl
Oxyal
Propine
Restasis
Tears
Tropicamide
Vistil


EyeDropsInfo.com © 2009 - 2012