Eye drops


Acular

Where to buy Acular ?

Structure


- 5 mg - Ketorolac Tromethamine USP
- 0.1 mg - Benzalkonium Chloride USP

Indications

Acular eye drops are indicated for the relief of ocular itching due to seasonal allergic conjunctivitis.

Contraindications

Acular eye drops are contraindicated in patients while wearing soft contact lenses and in patients who are hypersensitive to the medicine.

Pregnancy

Reproduction studies have been performed in rabbits, using daily oral doses at 3.6 mg/kg (42.35 mg/m2) and in rats at 10 mg/kg (59 mg/m2 during organogenesis. Results of these studies did not reveal evidence of teratogenicity to the foetus. Oral doses of Acular at 1.5 mg/kg (8.8 mg/m2) which was half of thc human oral exposure, administered after gestation day 17 caused dystocia and higher pup mortality in rats. There are no adequate and wellcontrolled studies in pregnant women. administered should be prescribed during pregnancy only if the potential benefit justifies the potential risk to the foetus.

Nursing Mothers

Caution should be exercised when Acular is administered to a nursing woman.

Side Effects

In patients with allergic conjunctivitis, the most frequent adverse events reported with the use of Acular have been transient stinging and burning on instillation. These events were reported by approximately 40% of patients treated with Acular.
In all development studies conducted, other adverse events reported during treatment with Acular include:
- Superficial ocular infections;
- Superficial keratitis;
- Ocular irritation;
- Allergic reactions;

Dosage

Acular eye drops recommended dose are 1 drop (0.25 mg) 4 times a day for relief of ocular itching due to seasonal allergic conjunctivitis. The efficacy of Acular has not been established beyond one week of therapy.

Form

Acular eye drops are available for topical ophthalmic administration as a 0.5% sterile solution, and is supplied in 5 ml plastic dropper bottles.

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